human EGLN2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human EGLN2.
shAAV-207664
AAV-h-EGLN2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human EGLN2 (egl-9 family hypoxia inducible factor 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
EIT6; HIF-PH1; HIFPH1; HPH-1; HPH-3; PHD1
Description (Vector)
The hypoxia inducible factor (HIF) is a transcriptional complex that is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this post-translational modification. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream RAB4B (RAB4B, member RAS oncogene family) gene.
Gene ID
112398
Gene Name (Vector)
egl-9 family hypoxia inducible factor 2
Gene Symbol
EGLN2
HGNC ID
HGNC:14660
ORF Size (aa)
1224
ORF Size (bp)
1224 bp
RefSeq ID
NM_080732
RefSeq Synonyms
NM_080732, NM_053046, BC036051,
Species
human
UniGene ID
Hs.515417
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.