mouse POLH Adenovirus

Name 
Ad-m-POLH
Cat No 
ADV-269017
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Mouse Polh.

ADV-269017
Ad-m-POLH

Ready-to-use Adenovirus expressing Mouse Polh (polymerase (DNA directed), eta (RAD 30 related)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
RAD30A; XPV
Description (Vector)
DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Plays an important role in the repair of UV-induced pyrimidine dimers. Depending on the context, it inserts the correct base, but causes frequent base transitions and transversions. May play a role in hypermutation at immunoglobulin genes. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but does not have lyase activity. Targets POLI to replication foci.
Gene ID
80905
Gene Name (Vector)
polymerase (DNA directed), eta (RAD 30 related)
Gene Symbol
Polh
ORF Size (aa)
1671
ORF Size (bp)
1671 bp
RefSeq ID
NM_030715
RefSeq Synonyms
NM_030715, BC128366,
Species
mouse
UniGene ID
Mm.311585

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.