mouse ENPP2 Adenovirus

Name 
Ad-m-ENPP2
Cat No 
ADV-258386
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human RETN.

ADV-258386
Ad-m-ENPP2

Ready-to-use Adenovirus expressing Mouse Enpp2 (ectonucleotide pyrophosphatase/phosphodiesterase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ATX; E-NPP 2; lysoPLD; Npps2; PD-Ialpha; Pdnp2
Description (Vector)
Hydrolyzes lysophospholipids to produce lysophosphatidic acid (LPA) in extracellular fluids. Major substrate is lysophosphatidylcholine. Also can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. Can hydrolyze, in vitro, bis-pNPP, to some extent pNP-TMP, and barely ATP. Involved in several motility-related processes such as angiogenesis and neurite outgrowth. Acts as an angiogenic factor by stimulating migration of smooth muscle cells and microtubule formation. Stimulates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein. May have a role in induction of parturition. Possible involvement in cell proliferation and adipose tissue development. Tumor cell motility-stimulating factor.
Gene ID
18606
Gene Name (Vector)
ectonucleotide pyrophosphatase/phosphodiesterase 2
Gene Symbol
Enpp2
ORF Size (aa)
2589
ORF Size (bp)
2589 bp
RefSeq ID
NM_015744
RefSeq Synonyms
NM_015744, NM_001285995, NM_001285994, NM_001136077, BC058759, BC003264,
Species
mouse
UniGene ID
Mm.250256

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.