human SIRT3 Adenovirus

Name 
Ad-h-SIRT3
Cat No 
ADV-223017
Availability
4-5 weeks

This is an Adenovirus expressing Human SIRT3.

ADV-223017
Ad-h-SIRT3

Ready-to-use Adenovirus expressing Human SIRT3 (sirtuin 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
SIR2L3
Description (Vector)
SIRT3 encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene.
Gene ID
23410
Gene Name (Vector)
sirtuin 3
Gene Symbol
SIRT3
HGNC ID
HGNC:14931
ORF Size (aa)
1200
ORF Size (bp)
1200 bp
RefSeq ID
NM_012239
RefSeq Synonyms
NM_012239, NM_001017524, BC001042,
Species
human
UniGene ID
Hs.716456

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.