human SCN11A Adenovirus
This is an Adenovirus expressing Human SCN11A.
ADV-222366
Ad-h-SCN11A
Ready-to-use Adenovirus expressing Human SCN11A (sodium voltage-gated channel alpha subunit 11). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
FEPS3; HSAN7; NaN; NAV1.9; PN5; SCN12A; SNS-2
Description (Vector)
Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits, such as SCN11A, mediate voltage-dependent gating and conductance, while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of disorders. Each alpha subunit consists of 4 domains connected by 3 intracellular loops; each domain consists of 6 transmembrane segments and intra- and extracellular linkers.(supplied by OMIM, Apr 2004)
Gene ID
11280
Gene Name (Vector)
sodium voltage-gated channel alpha subunit 11
Gene Symbol
SCN11A
HGNC ID
HGNC:10583
ORF Size (aa)
5373
ORF Size (bp)
5373 bp
RefSeq ID
NM_014139
RefSeq Synonyms
NM_014139, NM_001287223, BC172234,
Species
human
UniGene ID
Hs.591657
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.