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human IGF2BP2 Over-expression AAV

Name 
AAV-h-IGF2BP2
Cat No 
AAV-211920
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human IGF2BP2.

AAV-211920
AAV-h-IGF2BP2

Ready-to-use AAV expressing Human IGF2BP2 (insulin like growth factor 2 mRNA binding protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Hepatocellular carcinoma autoantigen p62; IGF2 mRNA-binding protein 2; IGF-II mRNA-binding protein 2; IMP2; IMP-2; insulin-like growth factor 2 mRNA-binding protein 2; VICKZ family member 2; VICKZ2
Description (eCommerce)
Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. Binding is isoform-specific and may regulate translation of target mRNAs [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9Y6M1].
Description (Vector)
IGF2BP2 encodes a member of the IGF-II mRNA-binding protein (IMP) family. The protein encoded by this gene contains several four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Gene ID
10644
Gene Name (eCommerce)
insulin like growth factor 2 mRNA binding protein 2
Gene Name (Vector)
insulin like growth factor 2 mRNA binding protein 2
Gene Symbol
IGF2BP2
HGNC ID
HGNC:28867
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1797
ORF Size (bp)
1797 bp
Protein Name (eCommerce)
Insulin-like growth factor 2 mRNA-binding protein 2
RefSeq ID
NM_006548
RefSeq Synonyms
NM_006548, NM_001291875, NM_001291874, NM_001291873, NM_001291872, NM_001291869, NM_001007225, BC021290,
Research Areas
Cytoskeleton,Gene Expression,mRNA Binding,mRNA transport,RNA Binding,RNA Transport,Translational Control
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. Binding is isoform-specific and may regulate translation of target mRNAs [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9Y6M1].
UniGene ID
Hs.35354
UniProt ID (eCommerce)
Q9Y6M1

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.