Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

NOS2

Gene Name

nitric oxide synthase 2

Gene ID

4843

Gene Synonyms

HEP-NOS; INOS; NOS; NOS2A

ORF Size

3462 bp

RefSeq#

BC130283

Gene Description

Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17.

UniGene ID

Hs.709191

HGNC ID

HGNC:7873