mouse FES shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-259328
Availability:
3-5 weeks
Name:
Ad-m-FES-shRNA
This is an Adenovirus expressing shRNA for silencing of Mouse Fes.
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Product Info
- Knockdown
- >70% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Fes
- Gene Name
- feline sarcoma oncogene
- Gene ID
- 14159
- Gene Synonyms
- AI586313; BB137047; c-fes; FPS
- ORF Size
- 2469 bp
- RefSeq#
- NM_010194
- Gene Description
- Tyrosine-protein kinase that acts downstream of cell surface receptors and plays a role in the regulation of the actin cytoskeleton, microtubule assembly, cell attachment and cell spreading. Plays a role in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Acts down-stream of the activated FCER1 receptor and the mast/stem cell growth factor receptor KIT. Plays a role in the regulation of mast cell degranulation. Plays a role in the regulation of cell differentiation and promotes neurite outgrowth in response to NGF signaling. Plays a role in cell scattering and cell migration in response to HGF-induced activation of EZR. Phosphorylates BCR and down-regulates BCR kinase activity. Phosphorylates HCLS1/HS1, PECAM1, STAT3 and TRIM28.
- UniGene ID
- Mm.48757
Related Products
Product | Cat No. |
---|---|
AAV-h-FES | AAV-208913 |
AAV-m-FES | AAV-259328 |
Ad-h-FES | ADV-208913 |
Ad-m-FES | ADV-259328 |
AAV-h-FES-shRNA | shAAV-208913 |
AAV-m-FES-shRNA | shAAV-259328 |
Ad-h-FES-shRNA | shADV-208913 |
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
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