human NAGLU Adenovirus
This is an Adenovirus expressing Human NAGLU.
ADV-216291
Ad-h-NAGLU
Ready-to-use Adenovirus expressing Human NAGLU (N-acetyl-alpha-glucosaminidase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CMT2V; MPS-IIIB; MPS3B; NAG; UFHSD
Description (Vector)
NAGLU encodes an enzyme that degrades heparan sulfate by hydrolysis of terminal N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides. Defects in this gene are the cause of mucopolysaccharidosis type IIIB (MPS-IIIB), also known as Sanfilippo syndrome B. This disease is characterized by the lysosomal accumulation and urinary excretion of heparan sulfate.
Gene ID
4669
Gene Name (Vector)
N-acetyl-alpha-glucosaminidase
Gene Symbol
NAGLU
HGNC ID
HGNC:7632
ORF Size (aa)
2232
ORF Size (bp)
2232 bp
RefSeq ID
NM_000263
RefSeq Synonyms
NM_000263, BC053991,
Species
human
UniGene ID
Hs.50727
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.