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human KIAA0652 Adenovirus

Name 
Ad-h-KIAA0652
Cat No 
ADV-212936
Availability
4-5 weeks

This is an Adenovirus expressing Human KIAA0652.

ADV-212936
Ad-h-KIAA0652

Ready-to-use Adenovirus expressing Human ATG13 (autophagy related 13). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ATG13 autophagy related 13 homolog; autophagy-related protein 13; KIAA0652; PARATARG8
Description (eCommerce)
Autophagy-related protein 13 (ATG13) is an autophagy factor required for autophagosome formation and mitophagy. It is a target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, ATG13 plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O75143].
Gene ID
9776
Gene Name (eCommerce)
autophagy related 13
Gene Name (Vector)
autophagy related 13
Gene Symbol
ATG13
HGNC ID
HGNC:29091
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1218
ORF Size (bp)
1218 bp
Protein Name (eCommerce)
Autophagy-related protein 13
RefSeq ID
NM_014741
RefSeq Synonyms
NM_014741, NM_001346360, NM_001346359, NM_001346358, NM_001346357, NM_001346356, NM_001346355, NM_001346354, NM_001346353, NM_001346352, NM_001346351, NM_001346350, NM_001346349, NM_001346348, NM_001346346, NM_001346344, NM_001346342, NM_001346340, NM_001346338, NM_001346337, NM_001346336, NM_001346335, NM_001346334, NM_001346333, NM_001346332, NM_001346331, NM_001346330, NM_001346329, NM_001346328, NM_001346327, NM_001346326, NM_001346325, NM_001346324, NM_001346323, NM_001346322, NM_001346321, NM_001346320, NM_001346319, NM_001346318, NM_001346317, NM_001346316, NM_001346315, NM_001346314, NM_001346313, NM_001346312, NM_001346311, NM_001205122, NM_001205121, NM_001205120, NM_001205119, NM_001142673, BC006191, BC002378, BC001331,
Research Areas
Autophagy,mTOR Signaling,Signal Transduction
Research Areas (Faceted)
cell_biology,signal_transduction
Species
human
Target Sentence
Autophagy-related protein 13 (ATG13) is an autophagy factor required for autophagosome formation and mitophagy. It is a target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, ATG13 plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O75143].
UniGene ID
Hs.127403
UniProt ID (eCommerce)
O75143

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.