human LTB Adenovirus

Name 
Ad-h-LTB
Cat No 
ADV-214659
Availability
4-5 weeks

This is an Adenovirus expressing Human EGR1.

ADV-214659
Ad-h-LTB

Ready-to-use Adenovirus expressing Human LTB (lymphotoxin beta). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
p33; TNFC; TNFSF3; TNLG1C
Description (Vector)
Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene ID
4050
Gene Name (Vector)
lymphotoxin beta
Gene Symbol
LTB
HGNC ID
HGNC:6711
ORF Size (aa)
735
RefSeq ID
NM_002341
RefSeq Synonyms
NM_009588, NM_002341, BC069330,
Species
human
UniGene ID
Hs.376208

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.