human CHEK1 Adenovirus
Category: Adenovirus > Over-Expression
Cat. No: ADV-205123
Availability:
3-5 weeks
Name:
Ad-h-CHEK1
This is an Adenovirus expressing Human CHEK1.
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Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- CMV
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- CHEK1
- Gene Name
- checkpoint kinase 1
- Gene ID
- 1111
- Gene Synonyms
- CHK1
- ORF Size
- 1431 bp
- RefSeq#
- BC004202
- Gene Description
- CHEK1 belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene.
- UniGene ID
- Hs.24529
- HGNC ID
- HGNC:1925
Related Products
Control Products
Product | Cat No. |
---|---|
Ad-CMV-Luc | 1000 |
Ad-GFP | 1060 |
Ad-CMV-b-Gal | 1080 |
Ad-Null | 1240 |
Ad-CMV-Null | 1300 |
Ad-RFP | 1660 |
Ad-CFP | 1766 |
Ad-mCherry | 1767 |
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