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human INTS7 shRNA silencing Adenovirus

Name 
Ad-h-INTS7-shRNA
Cat No 
shADV-212327
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human INTS7.

shADV-212327
Ad-h-INTS7-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human INTS7 (integrator complex subunit 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
83
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
C1orf73; INT7; integrator complex subunit 7
Description (eCommerce)
INT7 is subunit 7 of the integrator complex. The integrator complex is composed of at least 12 subunits and associates with the C-terminal domain of RNA polymerase II to mediate 3’-end processing of small-nuclear RNAs (snRNAs).
Description (Vector)
INTS7 encodes a subunit of the integrator complex. The integrator complex associates with the C-terminal domain of RNA polymerase II and mediates 3'-end processing of the small nuclear RNAs U1 and U2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
25896
Gene Name (eCommerce)
integrator complex subunit 7
Gene Name (Vector)
integrator complex subunit 7
Gene Symbol
INTS7
HGNC ID
HGNC:24484
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2889
ORF Size (bp)
2889 bp
Protein Name (eCommerce)
Integrator complex subunit 7
RefSeq ID
NM_015434
RefSeq Synonyms
NM_015434, NM_001199812, NM_001199811, NM_001199809, BC033918, BC030716, BC020523,
Research Areas
DNA Damage/Repair,RNA Processing
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
INT7 is subunit 7 of the integrator complex. The integrator complex is composed of at least 12 subunits and associates with the C-terminal domain of RNA polymerase II to mediate 3’-end processing of small-nuclear RNAs (snRNAs).
UniGene ID
Hs.369285
UniProt ID (eCommerce)
Q9NVH2

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.