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rat VTCN1 Over-expression AAV

Name 
AAV-r-VTCN1
Cat No 
AAV-294632
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Rat Vtcn1.

AAV-294632
AAV-r-VTCN1

Ready-to-use AAV expressing Rat Vtcn1 (V-set domain containing T cell activation inhibitor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
RGD1311204
Description (Vector)
Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation.
Gene ID
295322
Gene Name (Vector)
V-set domain containing T cell activation inhibitor 1
Gene Symbol
Vtcn1
ORF Size (aa)
849
RefSeq ID
NM_001024244
RefSeq Synonyms
NM_001024244, BC095842,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.