rat VTCN1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Rat Vtcn1.
shAAV-294632
AAV-r-VTCN1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Rat Vtcn1 (V-set domain containing T cell activation inhibitor 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
RGD1311204
Description (Vector)
Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation.
Gene ID
295322
Gene Name (Vector)
V-set domain containing T cell activation inhibitor 1
Gene Symbol
Vtcn1
ORF Size (aa)
849
RefSeq ID
NM_001024244
RefSeq Synonyms
NM_001024244, BC095842,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.