rat BCL2L1 Over-expression AAV

Name 
AAV-r-BCL2L1
Cat No 
AAV-292984
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Rat Bcl2l1.

AAV-292984
AAV-r-BCL2L1

Ready-to-use AAV expressing Rat Bcl2l1 (Bcl2-like 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
bcl-X; Bcl-xl; Bcl2l; Bclx
Description (Vector)
Potent inhibitor of cell death. Inhibits activation of caspases (By similarity). Appears to regulate cell death by blocking the voltage-dependent anion channnel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis|Function: Isoform Bcl-X(S) promotes apoptosis.
Gene ID
24888
Gene Name (Vector)
Bcl2-like 1
Gene Symbol
Bcl2l1
ORF Size (aa)
702
RefSeq ID
NM_001033670
RefSeq Synonyms
NM_031535, NM_001033672, NM_001033671, NM_001033670, BC094213,
Species
rat

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.