rat GIYD2 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-292480
Availability:
3-5 weeks
Name:
AAV-r-GIYD2
This is an AAV expressing Rat Slx1b.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Rat
- Gene Symbol
- Slx1b
- Gene Name
- SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
- Gene ID
- 293489
- Gene Synonyms
- Giyd1; Giyd2; LRRGT00058; RGD1311568
- ORF Size
- 816 bp
- RefSeq#
- BC087090
- Gene Description
- Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products.
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Control Products
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