rat AGTRAP Over-expression AAV

Name
AAV-r-AGTRAP

Cat No
AAV-290877

Availability
4-5 weeks

This is an AAV expressing Rat Agtrap.

AAV-290877

AAV-r-AGTRAP

Ready-to-use AAV expressing Rat Agtrap (angiotensin II receptor-associated protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalisation as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity.

Gene ID

298646

Gene Name (Vector)

angiotensin II receptor-associated protein

Gene Symbol

Agtrap

ORF Size (aa)

483

ORF Size (bp)

483 bp

RefSeq ID

NM_001007654

RefSeq Synonyms

NM_001007654, BC082019,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.