mouse AGTRAP shRNA silencing AAV

Cat. No: shAAV-252257

Availability: 4-5 weeks

Name: AAV-m-AGTRAP-shRNA

This is an AAV expressing shRNA for silencing of Mouse Agtrap.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Agtrap
Gene Name: angiotensin II, type I receptor-associated protein
Gene ID: 11610
Gene Synonyms: 3300002E14Rik; AT1R; Atrap; D4Wsu124e
ORF Size: 486 bp
RefSeq#: NM_009642
Gene Description: Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalisation as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity.
UniGene ID: Mm.46247