mouse AGTRAP shRNA silencing AAV

Name 
AAV-m-AGTRAP-shRNA
Cat No 
shAAV-252257
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Agtrap.

shAAV-252257
AAV-m-AGTRAP-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Agtrap (angiotensin II, type I receptor-associated protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
3300002E14Rik; AT1R; Atrap; D4Wsu124e
Description (Vector)
Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalisation as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity.
Gene ID
11610
Gene Name (Vector)
angiotensin II, type I receptor-associated protein
Gene Symbol
Agtrap
ORF Size (aa)
486
ORF Size (bp)
486 bp
RefSeq ID
NM_009642
RefSeq Synonyms
NM_009642, NM_001301281, BC057196, BC046820,
Species
mouse
UniGene ID
Mm.46247

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.