mouse ZC3HC1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-281217
Availability:
3-5 weeks
Name:
AAV-m-ZC3HC1
This is an AAV expressing Mouse Zc3hc1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Zc3hc1
- Gene Name
- zinc finger, C3HC type 1
- Gene ID
- 232679
- Gene Synonyms
- 1110054L24Rik; AU018540; AU019789; HSPC216; Nipa
- ORF Size
- 1506 bp
- RefSeq#
- BC050141
- Gene Description
- Essential component of an SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry. May have an antiapoptotic role in NPM-ALK-mediated signaling events.
- UniGene ID
- Mm.29780
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