mouse TRPA1 Over-expression AAV

Name 
AAV-m-TRPA1
Cat No 
AAV-275081
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Trpa1.

AAV-275081
AAV-m-TRPA1

Ready-to-use AAV expressing Mouse Trpa1 (transient receptor potential cation channel, subfamily A, member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Anktm1; TRPA1b
Description (Vector)
Receptor-activated non-selective cation channel involved in detection of pain and possibly also in cold perception and inner ear function. Has a central role in the pain response to endogenous inflammatory mediators and to a diverse array of volatile irritants, such as mustard oil, garlic and acrolein, an irritant from tears gas and vehicule exhaust fumes. Acts also as a ionotropic cannabinoid receptor by being activated by delta(9)-tetrahydrocannabinol (THC), the psychoactive component of marijuana. Not involved in menthol sensation. May be a component for the mechanosensitive transduction channel of hair cells in inner ear, thereby participating in the perception of sounds. Probably operated by a phosphatidylinositol second messenger system (By similarity).
Gene ID
277328
Gene Name (Vector)
transient receptor potential cation channel, subfamily A, member 1
Gene Symbol
Trpa1
ORF Size (aa)
3378
ORF Size (bp)
3378 bp
RefSeq ID
NM_177781
RefSeq Synonyms
NM_177781, BC131963, BC120563,
Species
mouse
UniGene ID
Mm.186329

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.