human SOCS4 Over-expression AAV

Name
AAV-h-SOCS4

Cat No
AAV-223976

Availability
4-5 weeks

This is an AAV expressing Human SOCS4.

AAV-223976

AAV-h-SOCS4

Ready-to-use AAV expressing Human SOCS4 (suppressor of cytokine signaling 4). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

SOCS7

Description (Vector)

SOCS4 contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.

Gene ID

122809

Gene Name (Vector)

suppressor of cytokine signaling 4

Gene Symbol

SOCS4

HGNC ID

HGNC:19392

ORF Size (aa)

1323

ORF Size (bp)

1323 bp

RefSeq ID

NM_080867

RefSeq Synonyms

NM_199421, NM_080867, BC060790,

Species

human

UniGene ID

Hs.708344

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.