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mouse TRPA1 shRNA silencing Adenovirus

Name 
Ad-m-TRPA1-shRNA
Cat No 
shADV-275081
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Trpa1.

shADV-275081
Ad-m-TRPA1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Trpa1 (transient receptor potential cation channel, subfamily A, member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Anktm1; TRPA1b
Description (Vector)
Receptor-activated non-selective cation channel involved in detection of pain and possibly also in cold perception and inner ear function. Has a central role in the pain response to endogenous inflammatory mediators and to a diverse array of volatile irritants, such as mustard oil, garlic and acrolein, an irritant from tears gas and vehicule exhaust fumes. Acts also as a ionotropic cannabinoid receptor by being activated by delta(9)-tetrahydrocannabinol (THC), the psychoactive component of marijuana. Not involved in menthol sensation. May be a component for the mechanosensitive transduction channel of hair cells in inner ear, thereby participating in the perception of sounds. Probably operated by a phosphatidylinositol second messenger system (By similarity).
Gene ID
277328
Gene Name (Vector)
transient receptor potential cation channel, subfamily A, member 1
Gene Symbol
Trpa1
ORF Size (aa)
3378
ORF Size (bp)
3378 bp
RefSeq ID
NM_177781
RefSeq Synonyms
NM_177781, BC131963, BC120563,
Species
mouse
UniGene ID
Mm.186329

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.