mouse TNFRSF10B Over-expression AAV
This is an AAV expressing Mouse Tnfrsf10b.
AAV-274689
AAV-m-TNFRSF10B
Ready-to-use AAV expressing Mouse Tnfrsf10b (tumor necrosis factor receptor superfamily, member 10b). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DR5; KILLER; Ly98; MK; TRAILR2; TRICK2A; TRICK2B; TRICKB
Description (Vector)
Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B.
Gene ID
21933
Gene Name (Vector)
tumor necrosis factor receptor superfamily, member 10b
Gene Symbol
Tnfrsf10b
ORF Size (aa)
1146
ORF Size (bp)
1146 bp
RefSeq ID
NM_020275
RefSeq Synonyms
NM_020275, BC065141,
Species
mouse
UniGene ID
Mm.193430
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.