mouse TNFRSF10B shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-274689
Availability:
3-5 weeks
Name:
Ad-m-TNFRSF10B-shRNA
This is an Adenovirus expressing shRNA for silencing of Mouse Tnfrsf10b.
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Product Info
- Knockdown
- >70% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Tnfrsf10b
- Gene Name
- tumor necrosis factor receptor superfamily, member 10b
- Gene ID
- 21933
- Gene Synonyms
- DR5; KILLER; Ly98; MK; TRAILR2; TRICK2A; TRICK2B; TRICKB
- ORF Size
- 1146 bp
- RefSeq#
- NM_020275
- Gene Description
- Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B.
- UniGene ID
- Mm.193430
Related Products
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
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