mouse TCF7 Over-expression AAV

Name 
AAV-m-TCF7
Cat No 
AAV-273923
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Tcf7.

AAV-273923
AAV-m-TCF7

Ready-to-use AAV expressing Mouse Tcf7 (transcription factor 7, T cell specific). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AI465550; TCF-1; Tcf1
Description (Vector)
Transcriptional activator involved in T-cell lymphocyte differentiation. Necessary for the survival of CD4(+) CD8(+) immature thymocytes. Isoforms lacking the N-terminal CTNNB1 binding domain cannot fulfill this role. Binds to the T-lymphocyte-specific enhancer element (5'-WWCAAAG-3') found in the promoter of the CD3E gene. May also act as feedback transcriptional repressor of CTNNB1 and TCF7L2 target genes. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7 and CTNNB1.
Gene ID
21414
Gene Name (Vector)
transcription factor 7, T cell specific
Gene Symbol
Tcf7
ORF Size (aa)
1005
RefSeq ID
NM_009331
RefSeq Synonyms
NM_009331, NM_001313981, BC145343, BC138596,
Species
mouse
UniGene ID
Mm.31630

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.