mouse SUV420H2 Over-expression AAV

Name 
AAV-m-SUV420H2
Cat No 
AAV-273488
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Kmt5c.

AAV-273488
AAV-m-SUV420H2

Ready-to-use AAV expressing Mouse Kmt5c (lysine methyltransferase 5C). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BC024816; Suv4-20h2; Suv420h2
Description (Vector)
Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2) (By similarity).
Gene ID
232811
Gene Name (Vector)
lysine methyltransferase 5C
Gene Symbol
Kmt5c
ORF Size (aa)
1062
ORF Size (bp)
1062 bp
RefSeq ID
NM_146177
RefSeq Synonyms
NM_146177, NM_001115018, BC085473, BC024816,
Species
mouse
UniGene ID
Mm.247844

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.