mouse SUV420H2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Kmt5c.
shAAV-273488
AAV-m-SUV420H2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Kmt5c (lysine methyltransferase 5C). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BC024816; Suv4-20h2; Suv420h2
Description (Vector)
Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2) (By similarity).
Gene ID
232811
Gene Name (Vector)
lysine methyltransferase 5C
Gene Symbol
Kmt5c
ORF Size (aa)
1062
ORF Size (bp)
1062 bp
RefSeq ID
NM_146177
RefSeq Synonyms
NM_146177, NM_001115018, BC085473, BC024816,
Species
mouse
UniGene ID
Mm.247844
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.