mouse NFKBIA Over-expression AAV

Name 
AAV-m-NFKBIA
Cat No 
AAV-265725
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Nfkbia.

AAV-265725
AAV-m-NFKBIA

Ready-to-use AAV expressing Mouse Nfkbia (nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AI462015; Nfkbi
Description (Vector)
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
Gene ID
18035
Gene Name (Vector)
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
Gene Symbol
Nfkbia
ORF Size (aa)
945
ORF Size (bp)
945 bp
RefSeq ID
NM_010907
RefSeq Synonyms
NM_010907, BC046754,
Species
mouse
UniGene ID
Mm.170515

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.