mouse NFKBIA shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Nfkbia.
shADV-265725
Ad-m-NFKBIA-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Nfkbia (nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AI462015; Nfkbi
Description (Vector)
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
Gene ID
18035
Gene Name (Vector)
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
Gene Symbol
Nfkbia
ORF Size (aa)
945
ORF Size (bp)
945 bp
RefSeq ID
NM_010907
RefSeq Synonyms
NM_010907, BC046754,
Species
mouse
UniGene ID
Mm.170515
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.