mouse LDLR Over-expression AAV

Name 
AAV-m-LDLR
Cat No 
AAV-263355
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Ldlr.

AAV-263355
AAV-m-LDLR

Ready-to-use AAV expressing Mouse Ldlr (low density lipoprotein receptor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Hlb301
Description (Vector)
Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. In case of HIV-1 infection, functions as a receptor for extracellular Tat in neurons, mediating its internalization in uninfected cells.
Gene ID
16835
Gene Name (Vector)
low density lipoprotein receptor
Gene Symbol
Ldlr
ORF Size (aa)
2589
ORF Size (bp)
2589 bp
RefSeq ID
NM_010700
RefSeq Synonyms
NM_010700, NM_001252659, NM_001252658, BC053041, BC019207,
Species
mouse
UniGene ID
Mm.3213

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.