mouse KCNQ2 Over-expression AAV

Name 
AAV-m-KCNQ2
Cat No 
AAV-262704
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse KCNQ2.

AAV-262704
AAV-m-KCNQ2

Ready-to-use AAV expressing Mouse KCNQ2 (potassium voltage-gated channel, subfamily Q, member 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HNSPC; KQT2; Nmf134
Description (Vector)
Probably important in the regulation of neuronal excitability. Associates with KCNQ3 to form a potassium channel with essentially identical properties to the channel underlying the native M-current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons as well as the responsiveness to synaptic inputs. KCNQ2/KCNQ3 current is blocked by linopirdine and XE991, and activated by the anticonvulsant retigabine. Muscarinic agonist oxotremorine-M strongly suppress KCNQ2/KCNQ3 current in cells in which cloned KCNQ2/KCNQ3 channels were coexpressed with M1 muscarinic receptors.
Gene ID
16536
Gene Name (Vector)
potassium voltage-gated channel, subfamily Q, member 2
Gene Symbol
KCNQ2
ORF Size (aa)
2610
ORF Size (bp)
2610 bp
RefSeq ID
NM_001006674
RefSeq Synonyms
NM_010611, NM_001302888, NM_001006680, NM_001006679, NM_001006678, NM_001006677, NM_001006676, NM_001006675, NM_001006674, NM_001006669, NM_001006668, NM_001003825, NM_001003824, BC156315, BC145453,
Species
mouse
UniGene ID
Mm.440175

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.