mouse IL28B Over-expression AAV

Name 
AAV-m-IL28B
Cat No 
AAV-262167
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Ifnl3.

AAV-262167
AAV-m-IL28B

Ready-to-use AAV expressing Mouse Ifnl3 (interferon lambda 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
IFL-1; IL-28B; Il28; Il28b; INF-alpha; INF-lambda
Description (Vector)
Cytokine with immunomodulatory activity. Up-regulates MHC class I antigen expression. Displays potent antiviral activity. Also displays antitumor activity. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.
Gene ID
338374
Gene Name (Vector)
interferon lambda 3
Gene Symbol
Ifnl3
ORF Size (aa)
582
ORF Size (bp)
582 bp
RefSeq ID
NM_177396
RefSeq Synonyms
NM_177396, BC141644, BC140273,
Species
mouse
UniGene ID
Mm.246799

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.