mouse HBXIP Over-expression AAV

Name 
AAV-m-HBXIP
Cat No 
AAV-261147
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Lamtor5.

AAV-261147
AAV-m-HBXIP

Ready-to-use AAV expressing Mouse Lamtor5 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
1110003H18Rik; Hbxip; XIP
Description (Vector)
When complexed to BIRC5, interferes with apoptosome assembly, preventing recruitment of pro-caspase-9 to oligomerized APAF1, thereby selectively suppressing apoptosis initiated via the mitochondrial/cytochrome c pathway. Down-regulates hepatitis B virus (HBV) replication.
Gene ID
68576
Gene Name (Vector)
late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
Gene Symbol
Lamtor5
ORF Size (aa)
276
RefSeq ID
NM_026774
RefSeq Synonyms
NM_026774, BC028547,
Species
mouse
UniGene ID
Mm.290035

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.