mouse HBXIP shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Lamtor5.
shAAV-261147
AAV-m-HBXIP-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Lamtor5 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1110003H18Rik; Hbxip; XIP
Description (Vector)
When complexed to BIRC5, interferes with apoptosome assembly, preventing recruitment of pro-caspase-9 to oligomerized APAF1, thereby selectively suppressing apoptosis initiated via the mitochondrial/cytochrome c pathway. Down-regulates hepatitis B virus (HBV) replication.
Gene ID
68576
Gene Name (Vector)
late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
Gene Symbol
Lamtor5
ORF Size (aa)
276
RefSeq ID
NM_026774
RefSeq Synonyms
NM_026774, BC028547,
Species
mouse
UniGene ID
Mm.290035
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.