mouse FREQ Over-expression AAV

Name 
AAV-m-FREQ
Cat No 
AAV-259627
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Ncs1.

AAV-259627
AAV-m-FREQ

Ready-to-use AAV expressing Mouse Ncs1 (neuronal calcium sensor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
9430075O15Rik; A730032G13Rik; AI836659; Freq; Mfreq; NCS-1
Description (Vector)
Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. Can substitute for calmodulin (By similarity). Stimulates PI4KB kinase activity (By similarity). Involved in long-term synaptic plasticity through its interaction with PICK1 (By similarity). May also play a role in neuron differentiation through inhibition of the activity of N-type voltage-gated calcium channel (By similarity).
Gene ID
14299
Gene Name (Vector)
neuronal calcium sensor 1
Gene Symbol
Ncs1
ORF Size (aa)
573
RefSeq ID
NM_019681
RefSeq Synonyms
NM_019681, BC059825,
Species
mouse
UniGene ID
Mm.249318

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.