mouse FLCN Over-expression AAV

Name 
AAV-m-FLCN
Cat No 
AAV-259466
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Flcn.

AAV-259466
AAV-m-FLCN

Ready-to-use AAV expressing Mouse Flcn (folliculin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AU014660; B430214A04Rik; Bhd; FLCL
Description (Vector)
FLCN may play a role in the pathogenesis of an uncommon form of kidney cancer through its association with an inherited disorder of the hair follicle (fibrofolliculomas). May be a tumor suppressor. May be involved in colorectal tumorigenesis. May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways. May regulate phosphorylation of RPS6KB1.
Gene ID
216805
Gene Name (Vector)
folliculin
Gene Symbol
Flcn
ORF Size (aa)
1740
ORF Size (bp)
1740 bp
RefSeq ID
NM_146018
RefSeq Synonyms
NM_146018, NM_001271357, NM_001271356, BC025820,
Species
mouse
UniGene ID
Mm.339640

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.