mouse FLCN shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Flcn.
shADV-259466
Ad-m-FLCN-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Flcn (folliculin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AU014660; B430214A04Rik; Bhd; FLCL
Description (Vector)
FLCN may play a role in the pathogenesis of an uncommon form of kidney cancer through its association with an inherited disorder of the hair follicle (fibrofolliculomas). May be a tumor suppressor. May be involved in colorectal tumorigenesis. May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways. May regulate phosphorylation of RPS6KB1.
Gene ID
216805
Gene Name (Vector)
folliculin
Gene Symbol
Flcn
ORF Size (aa)
1740
ORF Size (bp)
1740 bp
RefSeq ID
NM_146018
RefSeq Synonyms
NM_146018, NM_001271357, NM_001271356, BC025820,
Species
mouse
UniGene ID
Mm.339640
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.