mouse E4F1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-257682
Availability:
3-5 weeks
Name:
AAV-m-E4F1
This is an AAV expressing Mouse E4f1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- E4f1
- Gene Name
- E4F transcription factor 1
- Gene ID
- 13560
- Gene Synonyms
- p120E4F; phi-AP3
- ORF Size
- 2055 bp
- RefSeq#
- BC046459
- Gene Description
- E4F1 may function as a transcriptional repressor. May also function as a ubiquitin ligase mediating ubiquitination of chromatin-associated TP53. Functions in cell survival and proliferation through control of the cell cycle. Functions in the p53 and pRB tumor suppressor pathways and regulates the cyclin CCNA2 transcription|Function: Identified as a cellular target of the adenoviral oncoprotein E1A, it is required for both transcriptional activation and repression of viral genes.
- UniGene ID
- Mm.163132
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