mouse E4F1 shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-257683
Availability:
3-5 weeks
Name:
Ad-m-E4F1-shRNA
This is an Adenovirus expressing shRNA for silencing of Mouse E4f1.
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Product Info
- Knockdown
- >50% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- E4f1
- Gene Name
- E4F transcription factor 1
- Gene ID
- 13560
- Gene Synonyms
- p120E4F; phi-AP3
- ORF Size
- 1605 bp
- RefSeq#
- NM_007893
- Gene Description
- E4F1 may function as a transcriptional repressor. May also function as a ubiquitin ligase mediating ubiquitination of chromatin-associated TP53. Functions in cell survival and proliferation through control of the cell cycle. Functions in the p53 and pRB tumor suppressor pathways and regulates the cyclin CCNA2 transcription|Function: Identified as a cellular target of the adenoviral oncoprotein E1A, it is required for both transcriptional activation and repression of viral genes.
- UniGene ID
- Mm.163132
Related Products
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
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