mouse DDX42 Over-expression AAV

Name 
AAV-m-DDX42
Cat No 
AAV-256949
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Ddx42.

AAV-256949
AAV-m-DDX42

Ready-to-use AAV expressing Mouse Ddx42 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 42). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
1810047H21Rik; AW319508; AW556242; B430002H05Rik; RHELP; RNAHP; SF3b125
Description (Vector)
ATP-dependent RNA helicase. Binds to partially double-stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. Unwinding is promoted in the presence of single-strand binding proteins. Mediates also RNA duplex formation thereby displacing the single-strand RNA binding protein. ATP and ADP modulate its activity: ATP binding and hydrolysis by DDX42 triggers RNA strand separation, whereas the ADP-bound form of the protein triggers annealing of complementary RNA strands. Involved in the survival of cells by interacting with TP53BP2 and thereby counteracting the apoptosis-stimulating activity of TP53BP2. Relocalizes TP53BP2 to the cytoplasm.
Gene ID
72047
Gene Name (Vector)
DEAD (Asp-Glu-Ala-Asp) box polypeptide 42
Gene Symbol
Ddx42
ORF Size (aa)
2433
ORF Size (bp)
2433 bp
RefSeq ID
NM_028074
RefSeq Synonyms
NM_028074, BC043036,
Species
mouse
UniGene ID
Mm.41367

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.