mouse CFLAR Over-expression AAV

Name 
AAV-m-CFLAR
Cat No 
AAV-255341
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Cflar.

AAV-255341
AAV-m-CFLAR

Ready-to-use AAV expressing Mouse Cflar (CASP8 and FADD-like apoptosis regulator). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2310024N18Rik; A430105C05Rik; c-Flip; Cash; Casper; CLARP; ENSMUSG00000072980; FLAME; FLAME-1; Flip; Gm9845; I-FLICE; MRIT
Description (Vector)
Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. Acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity.
Gene ID
12633
Gene Name (Vector)
CASP8 and FADD-like apoptosis regulator
Gene Symbol
Cflar
ORF Size (aa)
1446
ORF Size (bp)
1446 bp
RefSeq ID
NM_009805
RefSeq Synonyms
NM_207653, NM_009805, NM_001293805, NM_001293804, NM_001289704, BC029223,
Species
mouse
UniGene ID
Mm.336848

Recently Viewed Products

AAV-ALB(1.4)-roGFP1

Cat No: VB1655

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.