mouse CCM2 Over-expression AAV

Name 
AAV-m-CCM2
Cat No 
AAV-254849
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Ccm2.

AAV-254849
AAV-m-CCM2

Ready-to-use AAV expressing Mouse Ccm2 (cerebral cavernous malformation 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BC029157
Description (Vector)
Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. May act through the stabilization of endothelial cell junctions (By similarity). May function as a scaffold protein for MAP2K3-MAP3K3 signaling. Seems to play a major role in the modulation of MAP3K3-dependent p38 activation induced by hyperosmotic shock (By similarity).
Gene ID
216527
Gene Name (Vector)
cerebral cavernous malformation 2
Gene Symbol
Ccm2
ORF Size (aa)
1362
ORF Size (bp)
1362 bp
RefSeq ID
NM_146014
RefSeq Synonyms
NM_146014, NM_001190344, NM_001190343, BC029157,
Species
mouse
UniGene ID
Mm.221271

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.