mouse CCM2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Ccm2.
shAAV-254849
AAV-m-CCM2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Ccm2 (cerebral cavernous malformation 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BC029157
Description (Vector)
Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. May act through the stabilization of endothelial cell junctions (By similarity). May function as a scaffold protein for MAP2K3-MAP3K3 signaling. Seems to play a major role in the modulation of MAP3K3-dependent p38 activation induced by hyperosmotic shock (By similarity).
Gene ID
216527
Gene Name (Vector)
cerebral cavernous malformation 2
Gene Symbol
Ccm2
ORF Size (aa)
1362
ORF Size (bp)
1362 bp
RefSeq ID
NM_146014
RefSeq Synonyms
NM_146014, NM_001190344, NM_001190343, BC029157,
Species
mouse
UniGene ID
Mm.221271
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.