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mouse ADAM17 Over-expression AAV

Name 
AAV-m-ADAM17
Cat No 
AAV-252041
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Adam17.

AAV-252041
AAV-m-ADAM17

Ready-to-use AAV expressing Mouse Adam17 (a disintegrin and metallopeptidase domain 17). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CD156b; Tace
Description (Vector)
Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1 and the amyloid precursor protein. Also involved in the activation of Notch pathway (By similarity).
Gene ID
11491
Gene Name (Vector)
a disintegrin and metallopeptidase domain 17
Gene Symbol
Adam17
ORF Size (aa)
2484
ORF Size (bp)
2484 bp
RefSeq ID
NM_009615
RefSeq Synonyms
NM_009615, NM_001291871, NM_001277266, BC145270, BC138420, BC138416, BC114999, BC094655,
Species
mouse
UniGene ID
Mm.27681

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.