mouse ADAM17 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-252041
Availability:
3-5 weeks
Name:
AAV-m-ADAM17
This is an AAV expressing Mouse Adam17.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Adam17
- Gene Name
- a disintegrin and metallopeptidase domain 17
- Gene ID
- 11491
- Gene Synonyms
- CD156b; Tace
- ORF Size
- 2484 bp
- RefSeq#
- BC114999
- Gene Description
- Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1 and the amyloid precursor protein. Also involved in the activation of Notch pathway (By similarity).
- UniGene ID
- Mm.27681
Related Products
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