human ADAM17 shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-200349
Availability:
4-5 weeks
Name:
AAV-h-ADAM17-shRNA
This is an AAV expressing shRNA for silencing of Human ADAM17.
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Product Info
- Knockdown
- >70% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- ADAM17
- Gene Name
- ADAM metallopeptidase domain 17
- Gene ID
- 6868
- Gene Synonyms
- ADAM18; CD156B; CSVP; NISBD; NISBD1; TACE
- ORF Size
- 2475 bp
- RefSeq#
- NM_003183
- Gene Description
- ADAM17 encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway.
- UniGene ID
- Hs.404914
- HGNC ID
- HGNC:195
Related Products
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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