human DVL1 Over-expression AAV

Name
AAV-h-DVL1

Cat No
AAV-230740

Availability
4-5 weeks

This is an AAV expressing Human DVL1.

AAV-230740

AAV-h-DVL1

Ready-to-use AAV expressing Human DVL1 (dishevelled segment polarity protein 1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

DRS2; DVL; DVL1L1; DVL1P1

Description (Vector)

DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.

Gene ID

1855

Gene Name (Vector)

dishevelled segment polarity protein 1

Gene Symbol

DVL1

HGNC ID

HGNC:3084

ORF Size (aa)

1335

ORF Size (bp)

1335 bp

RefSeq ID

NM_004421

RefSeq Synonyms

NM_004421, NM_001330311, BC050454,

Species

human

UniGene ID

Hs.719085

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.