human ZCCHC8 Over-expression AAV

Name 
AAV-h-ZCCHC8
Cat No 
AAV-228133
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ZCCHC8.

AAV-228133
AAV-h-ZCCHC8

Ready-to-use AAV expressing Human ZCCHC8 (zinc finger CCHC-type containing 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
TRAMP-like complex RNA-binding factor ZCCHC8; zinc finger CCHC domain-containing protein 8; zinc finger, CCHC domain containing 8
Description (eCommerce)
ZCCHC8 is a zinc-finger protein that bears a zinc-binding motif composed of a CX2CX4HX4C sequence (where X can be any amino acid). ZCCHC8 also bears a PSP domain, a proline rich domain found in numerous splicesome associated proteins. ZCCHC8 has been identified as a component of the splicesome C complex and as a substrate of glycogen synthase kinase-3. It is suggested to play a role in the processing and metabolism of RNA.
Gene ID
55596
Gene Name (eCommerce)
zinc finger CCHC-type containing 8
Gene Name (Vector)
zinc finger CCHC-type containing 8
Gene Symbol
ZCCHC8
HGNC ID
HGNC:25265
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2124
ORF Size (bp)
2124 bp
Protein Name (eCommerce)
Zinc finger CCHC domain-containing protein 8
RefSeq ID
NM_017612
RefSeq Synonyms
NM_017612, BC065918,
Research Areas
Gene Expression,mRNA Processing,mRNA Splicing,RNA Processing,Spliceosome,Zinc-finger
Research Areas (Faceted)
genetics,transcription_translation,cell_biology
Species
human
Target Sentence
ZCCHC8 is a zinc-finger protein that bears a zinc-binding motif composed of a CX2CX4HX4C sequence (where X can be any amino acid). ZCCHC8 also bears a PSP domain, a proline rich domain found in numerous splicesome associated proteins. ZCCHC8 has been identified as a component of the splicesome C complex and as a substrate of glycogen synthase kinase-3. It is suggested to play a role in the processing and metabolism of RNA.
UniGene ID
Hs.37706
UniProt ID (eCommerce)
Q6NZY4

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.