human ZCCHC8 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human ZCCHC8.
shAAV-228133
AAV-h-ZCCHC8-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human ZCCHC8 (zinc finger CCHC-type containing 8). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
TRAMP-like complex RNA-binding factor ZCCHC8; zinc finger CCHC domain-containing protein 8; zinc finger, CCHC domain containing 8
Description (eCommerce)
ZCCHC8 is a zinc-finger protein that bears a zinc-binding motif composed of a CX2CX4HX4C sequence (where X can be any amino acid). ZCCHC8 also bears a PSP domain, a proline rich domain found in numerous splicesome associated proteins. ZCCHC8 has been identified as a component of the splicesome C complex and as a substrate of glycogen synthase kinase-3. It is suggested to play a role in the processing and metabolism of RNA.
Gene ID
55596
Gene Name (eCommerce)
zinc finger CCHC-type containing 8
Gene Name (Vector)
zinc finger CCHC-type containing 8
Gene Symbol
ZCCHC8
HGNC ID
HGNC:25265
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2124
ORF Size (bp)
2124 bp
Protein Name (eCommerce)
Zinc finger CCHC domain-containing protein 8
RefSeq ID
NM_017612
RefSeq Synonyms
NM_017612, BC065918,
Research Areas
Gene Expression,mRNA Processing,mRNA Splicing,RNA Processing,Spliceosome,Zinc-finger
Research Areas (Faceted)
genetics,transcription_translation,cell_biology
Species
human
Target Sentence
ZCCHC8 is a zinc-finger protein that bears a zinc-binding motif composed of a CX2CX4HX4C sequence (where X can be any amino acid). ZCCHC8 also bears a PSP domain, a proline rich domain found in numerous splicesome associated proteins. ZCCHC8 has been identified as a component of the splicesome C complex and as a substrate of glycogen synthase kinase-3. It is suggested to play a role in the processing and metabolism of RNA.
UniGene ID
Hs.37706
UniProt ID (eCommerce)
Q6NZY4
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.