human UBXN11 Over-expression AAV

Name 
AAV-h-UBXN11
Cat No 
AAV-227090
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human UBXN11.

AAV-227090
AAV-h-UBXN11

Ready-to-use AAV expressing Human UBXN11 (UBX domain protein 11). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
COA-1; PP2243; SOC; SOCI; UBXD5
Description (Vector)
UBXN11 encodes a protein with a divergent C-terminal UBX domain. The homologous protein in the rat interacts with members of the Rnd subfamily of Rho GTPases at the cell periphery through its C-terminal region. It also interacts with several heterotrimeric G proteins through their G-alpha subunits and promotes Rho GTPase activation. It is proposed to serve a bidirectional role in the promotion and inhibition of Rho activity through upstream signaling pathways. The 3' coding sequence of this gene contains a polymoprhic region of 24 nt tandem repeats. Several transcripts containing between 1.5 and five repeat units have been reported. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
91544
Gene Name (Vector)
UBX domain protein 11
Gene Symbol
UBXN11
HGNC ID
HGNC:30600
ORF Size (aa)
975
RefSeq ID
NM_183008
RefSeq Synonyms
NM_183008, NM_145345, NM_001077262, BC038106,
Species
human
UniGene ID
Hs.145061

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.